COVID-19, Influenza, and RSV Wastewater Monitoring in the U.S. | Week of March 14, 2026

Summary: Week of 3/14/26

For the first time in months, all major respiratory viruses are decreasing. Biobot’s national network shows that Flu B and RSV, which had been holding on longer than COVID-19 and flu A, have finally turned a corner and are declining. COVID-19 and flu A have continued their steady decline and remain at low levels. This doesn’t mean the respiratory virus season is over, but it does mean we’re much closer to the end.

The Bottom Line: We are on the downward slope of the respiratory virus season, but we’re not quite done yet. Flu B and RSV will likely stay elevated for a few more weeks. For older adults, pregnant women, infants, and people with weakened immune systems, who remain at higher risk of severe illness, this is still a good time to layer protections. This could look like wearing a mask at the grocery store or on the train this week, or improving indoor ventilation with fans or air purifiers. Rapid flu and COVID-19 tests are now available at many pharmacies, so testing early can help people get treatment sooner.

National Outlook

COVID-19

Nationally, SARS-CoV-2 is decreasing.

Influenza

Nationally, influenza A and B are decreasing.

RSV

Nationally, RSV is decreasing.

Regional Outlook

The South

COVID-19: SARS-CoV-2 is decreasing in the South.

Influenza: Influenza A and B are decreasing in the South.

RSV: RSV is decreasing in the South.

The Midwest

COVID-19: SARS-CoV-2 is decreasing in the Midwest.

Influenza: Influenza A and B are decreasing in the Midwest.

RSV: RSV is decreasing in the Midwest.

The Northeast

COVID-19: SARS-CoV-2 is decreasing in the Northeast.

Influenza: Influenza A and B are decreasing in the Northeast.

RSV: RSV is decreasing in the Northeast.

The West

COVID-19: SARS-CoV-2 is decreasing in the West.

Influenza: Influenza A and B are decreasing in the West.

RSV: RSV is decreasing in the West.

Footnotes:

We continue to monitor the evolving H5N1 influenza virus situation, and can now test samples specifically for H5 (including H5N1) — please reach out to hello@biobot.io if interested. A quick reminder that Biobot’s influenza A assay described in this report includes the H5N1 influenza subtype, which is an influenza A virus, but does not distinguish between the different subtypes of influenza A (e.g. H5N1 vs H1N1). We will share any important updates as we have them. 

Wastewater data from Biobot Analytics for RSV, influenza, and SARS-CoV-2 are through March 14, 2026 (MMWR week 10).