Summary: Week of 5/3/25
Biobot’s national wastewater network shows that COVID-19, influenza A, and influenza B are declining in week 18 (through May 3, 2025), while RSV is holding steady at low levels. National hospitalizations for COVID-19, influenza, and RSV continue to decrease, currently at 1.2, 0.6, and 0.3 per 100,000 people in week 17 (through April 26, 2025).
The Bottom Line: We are almost at the end of the respiratory season but some flu B activity lingers— we can expect a couple of more weeks of transmission. It’s good to remember these recommendations to stay healthy: stay current with vaccinations, consider wearing a mask in crowded areas, and if you feel unwell, minimize contact with others.
National Outlook
COVID-19
National SARS-CoV-2 concentrations are declining.
Influenza
National flu A & B concentrations are declining.
RSV
National RSV concentrations are holding steady at low levels.
Regional
The South
COVID-19: SARS-CoV-2 concentrations are declining in the South
Influenza: Influenza A concentrations are holding steady at very low levels in the South, while influenza B is fluctuating at low levels.
RSV: RSV concentrations are holding steady at low levels in the South.
The Midwest
COVID-19: SARS-CoV-2 concentrations are declining in the Midwest.
Influenza: Influenza A concentrations are holding steady at very low levels in the Midwest, while influenza B is declining.
RSV: RSV concentrations are slightly increasing in the Midwest, but remain low.
The Northeast
COVID-19: SARS-CoV-2 concentrations are declining in the Northeast.
Influenza: Influenza A concentrations are holding steady at very low levels in the Northeast, while influenza B is declining.
RSV: RSV concentrations are holding steady at low levels in the Northeast.
The West
COVID-19: SARS-CoV-2 concentrations are slightly increasing in the West, but remain low.
Influenza: Influenza A concentrations are holding steady at very low levels in the West, while influenza B is fluctuating at low levels.
RSV: RSV concentrations are holding steady at low levels in the West.
Footnotes:
We continue to monitor the evolving H5N1 influenza virus situation, and can now test samples specifically for H5 (including H5N1) — see our blog here and please reach out to hello@biobot.io if interested. A quick reminder that Biobot’s influenza A assay described in this report includes the H5N1 influenza subtype, which is an influenza A virus, but does not distinguish between the different subtypes of influenza A (e.g. H5N1 vs H1N1). We will share any important updates as we have them via Bluesky and in the risk reports.
Wastewater data from Biobot Analytics for RSV, influenza, and SARS-CoV-2 are through May 3, 2025 (MMWR week 18). Clinical data for RSV, influenza, and COVID-19 are from the Centers for Disease Control and Prevention. Updates to clinical data are through April 26, 2025 (MMWR week 17).